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目的探讨哈密地区维吾尔族与汉族前列腺癌患者年龄、血清特异性抗原(TPAS)及相关变数、前列腺体积(PV)、Gleason评分的民族差异性。方法收集2005年1月-2015年1月在哈密地区中心医院确诊的前列腺癌患者共98例,其中维吾尔族40例,汉族58例。采用病例对照的方法分析维、汉族前列腺癌患者的年龄、TPSA、游离血清前列腺特异性抗原(FPSA)、F/T、PV、前列腺特异性抗原密度(PSAD)及Gleason评分的差异性。结果 1、维、汉族前列腺癌患者在年龄、FPSA及F/T值的差异均具有统计学意义(P均<0.05),PSA、PV、PSAD及Gleason评分的差异均无统计学意义(P均>0.05)。2、年龄≥65岁或F/T≤0.16时,维、汉两族前列腺癌患者分布差异明显。(P<0.05,R R=3.168;P<0.05,R R=2.451)。结论新疆哈密地区维、汉两民族前列腺癌患者在年龄、FPSA、F/T值存在差异,同地区不同民族前列腺癌患者F/T的临界值需进一步探讨。
Objective To investigate the ethnic differences of age, serum specific antigen (TPAS), related variables, prostatic volume (PV) and Gleason score between Uygur and Han nationality in Hami area. Methods A total of 98 cases of prostate cancer diagnosed in Central Hospital of Hami from January 2005 to January 2015 were collected, of which 40 cases were Uygur and 58 cases were Han nationality. The case-control method was used to analyze the differences of age, TPSA, FPSA, F / T, PV, PSAD and Gleason scores between the two groups. There was no significant difference in the PSA, PV, PSAD and Gleason scores between the two groups (P <0.05). There was no significant difference in the age, FPSA and F / T between the two groups > 0.05). 2, age ≥ 65 years old or F / T ≤ 0.16, the two groups of patients with prostate cancer distribution was significantly different. (P <0.05, R R = 3.168; P <0.05, R R = 2.451). Conclusions There are differences in age, FPSA and F / T between prostate cancer patients of Han and Uygur ethnic groups in Hami area of Xinjiang. The critical value of F / T in patients with prostate cancer of different nationalities in the same area should be further explored.