论文部分内容阅读
目的探讨可逆性后部脑病综合征(RPES)的临床、影像学特点及与预后的相关性。方法对8例明确为RPES患者的临床、影像学及预后资料做回顾性分析。结果 8例患者主要表现为头痛、血压高、视觉障碍,可伴有抽搐、意识障碍。6例核磁共振DWI为低或稍高信号,表观弥散系数(ADC)图高信号,预后良好;2例延误治疗患者DWI高信号,ADC图低信号,预后不良。结论 RPES为临床少见的可逆性神经系统损害疾病。影像上主要表现为后循环区域的异常病灶。以血管源性脑水肿为病理基础,积极治疗后可治愈,治疗不及时,发展为细胞毒性脑水肿,影像上表现为DWI高信号,ADC图低信号者,预后不良。
Objective To investigate the clinical features and prognosis of reversible posterior encephalopathy syndrome (RPES). Methods Retrospective analysis of 8 cases of RPES patients with clinical, radiographic and prognostic data. Results 8 patients mainly manifested as headache, high blood pressure, visual impairment, may be associated with convulsions, disturbance of consciousness. 6 cases of DWI was low or slightly high signal, apparent diffuse coefficient (ADC) high signal, the prognosis was good; 2 patients with delayed treatment of DWI high signal, ADC low signal, poor prognosis. Conclusion RPES is a rare clinical reversible neurological damage. The image is mainly manifested as abnormalities in the posterior circulation area. Vascular brain edema as the pathological basis of active treatment can be cured, the treatment is not timely, the development of cytotoxic brain edema, the image showed high DWI, ADC low signal, poor prognosis.