孕母血中循环的胎儿细胞是作为无创伤性产前诊断的重要选择细胞,为了评价培养母血中胎儿有核红细胞作为无创伤性产前诊断的可行性。作者采集了27例9～17周孕妇外周血标本,每例标本分为两组,一组在培养前用了磁场细胞分离装置(Macs)分离单个核细胞,另一组则没有分离;其中16例获得了足够的单个核细胞。将Macs分离出的有核细胞接种于含多种生长因子的半固体培养基中,而未经Macs分离的另一组细胞接 Fetal cells circulating in maternal blood are an important candidate for noninvasive prenatal diagnosis. To evaluate the feasibility of fetal nucleated erythrocytes in maternal blood as a non-invasive prenatal diagnosis. The authors collected 27 pregnant women 9 to 17 weeks of peripheral blood samples, each sample was divided into two groups, one group before the use of magnetic field separation devices (Macs) isolated mononuclear cells, the other group did not separate; of which 16 Example obtained enough mononuclear cells. The nucleated cells isolated from Macs were inoculated into semi-solid media containing a variety of growth factors, while another group of cells not isolated from Macs