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目的评价阿仑磷酸钠治疗绝经后妇女骨质疏松症的疗效。方法对72例患骨质疏松症的绝经后妇女随机分为阿仑磷酸钠组42例和钙尔奇D组30例治疗,治疗前两组性别、年龄、疼痛症状等方面均无显著差异,阿仑磷酸钠组服用阿仑磷酸钠10 mg,1次/日,晨起空腹服;钙尔奇D组服用钙尔奇D1片,1次/日,晚餐后服用,疗程均为6个月。测定治疗前后腰椎骨密度,观察临床症状和体征改善情况。结果阿仑磷酸钠治疗组骨密度定量测定有明显提高,疼痛症状改善明显,疼痛改善时间明显缩短,总有效率95.3%;钙尔奇D组总有效率43.3%,P<0.05。结论阿仑磷酸钠治疗绝经后妇女骨质疏松症疗效明确。
Objective To evaluate the efficacy of alendronate in the treatment of postmenopausal women with osteoporosis. Methods Seventy-two postmenopausal women with osteoporosis were randomly divided into alendronate group (n = 42) and Caerchief group (n = 30). There were no significant differences in gender, age and pain before treatment between the two groups. Alendronate sodium group was given alendronate 10 mg once a day, morning fasting service; Calcium odd D group taking Calcium D1 tablets, once daily, after dinner, both for 6 months . Lumbar bone mineral density was measured before and after treatment to observe the clinical symptoms and signs of improvement. Results The BMD of alendronate group was significantly higher than that of the control group (P <0.05). The pain symptom was significantly improved and the pain relief time was significantly shortened. The total effective rate was 95.3%. The total effective rate was 43.3%. Conclusion Alendronate is effective in treating postmenopausal women with osteoporosis.