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病例报告男,41岁,住院号234379。因心慌、气短12年,全身黄染3天,于1986年6月19日住院。12年前出现心慌、气短及反复双下肢浮肿,在本院诊断为:“风湿性心脏病、二尖瓣狭窄”。入院前4天上述症状加重,体温38℃,咳嗽,黄白色痰。在院外用洋地黄、红霉素1.2克静滴。在用药过程中,出现全身搔痒、荨麻疹,体温升至39.2℃,故停止输液。1天后出现恶心、呕吐,全身皮肤及巩膜黄染。既往史:1年前曾静滴过1次红霉素出现过上述症状但无黄染。无肝炎接触史;青霉素、磺胺药过敏。个人、家族史无异常。查体:体温38.9℃,脉搏82次/分,呼吸22次/
Case report Male, 41 years old, hospital number 234379. Due to palpitation, shortness of breath for 12 years, body yellow dye for 3 days, in June 19, 1986 hospitalization. 12 years ago, palpitation, shortness of breath and repeated lower extremity edema, diagnosed in our hospital as: “rheumatic heart disease, mitral stenosis.” 4 days before admission the above symptoms worse, body temperature 38 ℃, cough, yellow-white sputum. In the hospital with digitalis, erythromycin 1.2 grams of intravenous infusion. In the course of medication, there systemic itching, urticaria, body temperature rose to 39.2 ℃, it stopped infusion. After 1 day, nausea, vomiting, yellowing of the whole body skin and sclera. Past history: 1 year ago had intravenous infusion of erythromycin appeared above symptoms but no yellow dye. No history of hepatitis exposure; penicillin, sulfa drugs allergy. Personal, family history without exception. Physical examination: body temperature 38.9 ℃, pulse 82 beats / min, breathing 22 times /