Failure to disengage PI—3K pathway signaling confers Anti—IgM resistance to growth arrest and apopto

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【正】We and others have firmly established that surface IgM receptor (sIgM-R) crosslinking with antibodies to the i heavy chain (anti-i) leads to growth arrest and apoptosis in a series of well characterized B-cell lymphomas. This requires ablation of c-Myc
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