【摘 要】
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The title compound,5-methoxy-butyrolacto[3,4-b]-l-N-cyclohexylaziridine 1,has been synthesized via tandem Micheal addition and intramolecular nucleophilic subst
【机 构】
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Department of Chemistry
论文部分内容阅读
The title compound,5-methoxy-butyrolacto[3,4-b]-l-N-cyclohexylaziridine 1,has been synthesized via tandem Micheal addition and intramolecular nucleophilic substitution reactions of 5-methoxy-3-bromo-2(5H)-furanones 4 with primary amines 5,and structurally determined by single-crystal X-ray diffraction.Crystal data: C11H17NO3,Mr = 211.26,monoclinic system,space group P21/c,a = 17.800(3),b = 5.3864(10),c = 12.2571(10)(。A),β= 90.449(3)°,V= 1175.1(3)(。A)3,Z = 4,Dc= 1.194 g/cm3,λ(MoKα) = 0.071073 nm,μ = 0.087 mm～1 and F(000) = 456.The structure was refined to R = 0.0505 and wR = 0.1208 for 2579 observed reflections (I ＞ 2σ(I)).The crystallographic results of molecule 1 show that the functionalized aziridine ring is fused with a lactone ring to form the component with [3.1.0] bicyclic skeleton.
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