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目的:探讨脐血干细胞静脉输注对失代偿期肝硬化的临床治疗效果。方法:患者为慢性重症肝炎、肝硬化失代偿期,采用脐血干细胞静脉输注治疗共2次,治疗后半年观察血清转氨酶(ALT)、天门冬氨酸氨基转移酶(AST)、r-谷氨酰转肽酶(GGT)、白蛋白(ALB)、总胆红素(TBIL)、结合胆红素(DBIL)、非结合胆红素(IBIL)、凝血酶原时间(PT)水平变化,同时观察临床症状、体征改善情况。结果:各项实验室指标逐渐正常,腹水消退,临床症状明显改善。结论:脐血干细胞静脉输注治疗失代偿期肝硬化安全、简便、有效。
Objective: To investigate the clinical effect of intravenous infusion of cord blood stem cells on decompensated cirrhosis. Methods: The patients were chronic severe hepatitis and decompensated liver cirrhosis. The umbilical cord stem cells were infused intravenously for 2 times. After six months of treatment, the levels of serum aminotransferase (ALT), aspartate aminotransferase (AST), r- (GGT), albumin (ALB), total bilirubin (TBIL), bound bilirubin (DBIL), unconjugated bilirubin (IBIL), prothrombin time (PT) , While observing clinical symptoms, signs of improvement. Results: The laboratory indicators gradually normal, ascites subsided, clinical symptoms improved significantly. Conclusion: Intravenous infusion of umbilical cord blood stem cells in the treatment of decompensated cirrhosis is safe, simple and effective.