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目的:研究血清CA125和CA199的测定对卵巢疾病和胰腺疾病诊断的临床意义。方法:发光免疫分析测定了50例正常对照组,95例卵巢疾病和67例胰腺疾病患者血清中CA125和CA199的水平。结果:卵巢癌与胰腺癌患者的血清CA125和CA199水平较对照组显著升高(P<0.001)。结论:血清CA125和CA199联合测定对诊断和鉴别卵巢癌和胰腺癌有一定的临床价值。
Objective: To study the clinical significance of the determination of serum CA125 and CA199 in the diagnosis of ovarian disease and pancreatic diseases. Methods: The levels of CA125 and CA199 in sera of 50 normal controls, 95 cases of ovarian diseases and 67 cases of pancreatic diseases were determined by luminescence immunoassay. Results: Serum levels of CA125 and CA199 in patients with ovarian cancer and pancreatic cancer were significantly higher than those in the control group (P <0.001). Conclusion: The combined determination of serum CA125 and CA199 has certain clinical value in the diagnosis and differential diagnosis of ovarian cancer and pancreatic cancer.