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晚期中央型肺癌病人全身化疗效果差,毒副作用大,而放射治疗也有较大的副作用。目前国内外已开展了经纤维支气管镜(以下简称纤支镜)介导抗癌法,其中之一是将抗癌药经过纤支镜直接注射到肿瘤局部,使抗癌药在肿瘤局部达到最高浓度,延长作用时间,从而有效杀死癌细胞,也可减轻全身毒副作用,常规化疗药物大部分都适用于局部化疗。在本研究中,2002年以来,我们将抗癌药羟基喜树碱注射到肿瘤局部治疗中央型肺癌,取得了较好的疗效。1 资料与方法1.1 临床病例本组病例共46例,随机分成2组,
Late-stage central lung cancer patients have poor systemic chemotherapy and toxic side effects, while radiation therapy also has major side effects. At present, anti-cancer methods mediated by fiberoptic bronchoscopes (hereinafter referred to as fiberbronchoscopes) have been developed at home and abroad. One of them is the direct injection of anticancer drugs through the bronchoscope to the tumor site, so that the anticancer drug reaches the maximum in the tumor area. Concentration, prolong the time of action, thereby effectively killing cancer cells, can also reduce the systemic side effects, most conventional chemotherapy drugs are applicable to local chemotherapy. In this study, since 2002, we have injected the anticancer drug hydroxycamptothecine into the local treatment of central lung cancer and achieved good results. 1 Materials and Methods 1.1 Clinical Cases A total of 46 cases were randomly divided into 2 groups.