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目的探讨D-D二聚体对缺血性结肠炎病变范围的预测价值。方法选取安徽医科大学第二附属医院2011年6月—2016年6月收治的缺血性结肠炎患者51例,根据病变累及范围将所有患者分为单一肠段组36例和多肠段组15例。统计比较两组患者的性别、基础疾病、年龄、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、D-D二聚体、纤维蛋白原(FIB)、血小板计数(PLT)、三酰甘油(TG)、总胆固醇(TC)。结果两组患者性别、合并基础疾病率、PT、APTT、FIB、PLT、TG、TC比较,差异无统计学意义(P>0.05);多肠段组患者年龄、D-D二聚体水平高于单一肠段组(P<0.05)。logistic多因素分析结果显示,D-D二聚体是缺血性结肠炎病变范围的危险因素(P<0.05)。结论 D-D二聚体是缺血性结肠炎病变范围的危险因素,可作为预测缺血性结肠炎患者病变范围的指标。
Objective To investigate the predictive value of D-D dimer in the range of ischemic colitis. Methods Fifty-one patients with ischemic colitis admitted to the Second Affiliated Hospital of Anhui Medical University from June 2011 to June 2016 were enrolled. All patients were divided into single bowel segment group (36 cases) and multiple bowel segment group (15) according to the extent of lesion involvement example. The gender, underlying disease, age, PT, APTT, DD dimer, fibrinogen (FIB), platelet count Acylglycerol (TG), total cholesterol (TC). Results There was no significant difference in gender, combined basic disease rate, PT, APTT, FIB, PLT, TG and TC between the two groups (P> 0.05) Intestinal segment group (P <0.05). Logistic multivariate analysis showed that D-D dimer was a risk factor for the range of ischemic colitis (P <0.05). Conclusion D-D dimer is a risk factor for the range of ischemic colitis, and can be used as an index to predict the extent of disease in patients with ischemic colitis.