目的:探讨心肺复苏机在急性冠脉综合征致心脏骤停患者超长心肺复苏中的效果。方法:收集2014年5月至2016年5月,广州市第一人民医院因急性冠脉综合征诱发心脏骤停且在最初30 min标准化心肺复苏未恢复自主循环的患者95例,在机械通气和规范抢救流程基础上,随机分为人工胸外按压组48例和心肺复苏机组47例。对比两组患者的自主循环恢复率和存活出院率2项指标。结果:心肺复苏机组在30~60 min和60~120 min这2个复苏时长内,抢救自主循环恢复率和出院存活率均高于人工按压组,差异具有统计学意义(P<0.05)。另有2例患者复苏时长超过120 min,其中1例自主循环恢复,未能出院存活。结论:急诊室内急性冠脉综合征导致的心脏骤停患者采用心肺复苏机在超长心肺复苏中比人工胸外按压有更高的自主循环恢复率和出院存活率。 Objective: To investigate the effect of cardiopulmonary resuscitation on long cardiopulmonary resuscitation in patients with cardiac arrest caused by acute coronary syndrome. Methods: From May 2014 to May 2016, 95 cases of patients with cardiac arrest caused by acute coronary syndrome and no standardized cardiopulmonary resuscitation in the first 30 min in Guangzhou First People’s Hospital were enrolled. After mechanical ventilation and On the basis of standardized rescue procedures, they were randomly divided into 48 cases of artificial chest compression group and 47 cases of cardiopulmonary resuscitation unit. The two groups of patients compared the recovery rate of spontaneous circulation and survival rate of two indicators. Results: The resuscitation recovery rate and discharge survival rate of CPR units were significantly higher than those of manual compression groups at 30-60 min and 60-120 min (P <0.05). Another two patients recovered more than 120 min, of which 1 recovered spontaneously and failed to discharge. Conclusion: Cardiopulmonary resuscitation (CPR) patients with sudden cardiac arrest due to acute coronary syndrome in emergency room have a higher rate of spontaneous circulation recovery and discharge than that of artificial chest compression in long-term cardiopulmonary resuscitation.