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选取我院收治的120例T_2DM患者,将其均分为对照组给予二甲双胍片治疗,观察组在对照组基础上给予西格列汀治疗。结果:治疗后,两组FBG、2hPG、HbA_(1c)水平较治疗前均降低(P<0.05),观察组下降较为显著(P<0.05);观察出现胃肠道反应2例(3.33%)比对照组低(P<0.05),其总不良反应率也显著低于对照组(P<0.05)。结论:西格列汀联合二甲双胍治疗T_2DM效果理想。
Select 120 cases of T_2DM patients admitted to our hospital, divided into control group were treated with metformin tablets, the observation group on the basis of the control group were given sitagliptin. Results: After treatment, the levels of FBG, 2hPG and HbA_ (1c) in both groups were significantly lower than those before treatment (P <0.05), and the decrease was significant in the observation group (P <0.05) (P <0.05), and the total adverse reaction rate was also significantly lower than that of the control group (P <0.05). Conclusion: Sitagliptin combined with metformin in T 2DM is effective.