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外周血中人甲状腺球蛋白(HTG)只能来源于功能性甲状腺组织,甲状腺癌患者因切除了甲状腺,故循环中应无HTG。若HTG重新出现则是甲状腺癌复发的特异标志。作者对30例因分化型甲状腺癌而切除甲状腺二年以上的患者血清HTG水平与~(131)Ⅰ全身显像进行了研究。材料与方法:HTG纯化是按修改的Van Herle氏法进行。~(135)Ⅰ-标记HTG制备是用乳过氧化酶法标
Human peripheral blood thyroglobulin (HTG) can only be derived from functional thyroid tissue, patients with thyroid cancer due to the removal of the thyroid, so there should be no circulating HTG. If HTG is re-emerged thyroid cancer recurrence is a specific marker. The authors studied serum HTG levels and ~ (131) I whole body imaging in 30 patients with differentiated thyroid cancer who had undergone thyroidectomy for more than two years. Materials and Methods: HTG purification was performed according to the modified Van Herle’s method. The ~ (135) I-labeled HTG was prepared by lactoperoxidase