铁在体内分布十分广泛,参与其代谢的蛋白质包括血红蛋白、铁蛋白、转铁蛋白等,虽然对外周组织铁的代谢及调控机制在分子、基因水平上取得了一定进展,但是中枢神经系统的铁代谢过程尚不清楚。临床及实验研究表明中枢神经系统中铁代谢的紊乱与一些神经病变有关,如阿尔兹海默病(AD Iron is widely distributed in the body, and the proteins involved in its metabolism include hemoglobin, ferritin and transferrin. Although the metabolism and regulation mechanisms of iron in peripheral tissues have made some progress at the molecular and genetic levels, iron in the central nervous system The metabolic process is not clear. Clinical and experimental studies have shown that disorders of iron metabolism in the central nervous system are associated with several neuropathies such as Alzheimer’s disease (AD