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目的:研究原发性胃肠道T细胞淋巴瘤临床病理特征及预后相关因素。方法:回顾性分析2008年1月至2013年12月期间我院收治的胃肠道T细胞淋巴瘤患者26例的临床资料。结果 :本组26例中,男∶女=1.17∶1,首发症状以消化道症状为主(42.3%),病变部位以肠道为主(73.1%)。患者3年生存率为15.4%,生存因素分析表明年龄、首发症状、病变直径、LDH升高与否、临床分期因素与预后相关(P<0.05)。结论:原发性胃肠道T细胞淋巴瘤是一组预后不良的疾病,其预后与年龄、首发症状、病变直径、LDH升高与否、临床分期因素等相关。
Objective: To study the clinicopathological features and prognostic factors of primary gastrointestinal T-cell lymphoma. Methods: The clinical data of 26 patients with gastrointestinal T-cell lymphoma treated in our hospital from January 2008 to December 2013 were retrospectively analyzed. Results: The group of 26 patients, male: female = 1.17: 1, the first symptom of gastrointestinal symptoms (42.3%), mainly intestinal lesions (73.1%). The 3-year survival rate of patients was 15.4%. Analysis of survival factors showed that age, initial symptoms, diameter of lesions, elevated LDH or not, and clinical stage were correlated with prognosis (P <0.05). Conclusions: Primary gastrointestinal T-cell lymphoma is a group of poor prognosis. Its prognosis is related to age, initial symptom, pathological diameter, elevated LDH or clinical stage.