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用抗T细胞、B细胞,组织细胞及Ki-1抗原单克隆抗体对58例大细胞性淋巴瘤的石蜡切片进行染色,并与组织学改变加以比较。结果发现58例中B细胞性43例(74.1％),外周T细胞性15例(25.9％)。其中2例B,1例T细胞瘤形态学上为大细胞间变性,并为Ki-1阳性。外周T细胞淋巴瘤的有价值的形态改变为粉尘状染色质,中等大小的嗜酸性核仁,浅染胞浆,血管增生及嗜酸性细胞浸润。大细胞B淋巴瘤则为边集粗糙之染色质,嗜碱性核仁及浆细胞分化。
Paraffin sections from 58 cases of large cell lymphoma were stained with anti-T cells, B cells, tissue cells and monoclonal antibodies to Ki-1 antigen and compared with histological changes. The results showed that 58 cases of B cells in 43 cases (74.1%), peripheral T cell in 15 cases (25.9%). Two of them, B, and 1 T-cell tumor were morphologically large-cell degeneration and were Ki-1 positive. The valuable morphological changes of peripheral T-cell lymphomas are dusty chromatin, moderately sized eosinophilic nucleoli, lightly stained cytoplasm, vascular hyperplasia and eosinophilic infiltration. Large cell B lymphoma is a set of rough chromatin, basophilic nucleolus and plasma cell differentiation.