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目的探讨急性非梗阻性胆源性胰腺炎的发病原因。方法回顾分析126例急性非梗阻性胆源性胰腺炎患者的临床资料和影像资料,了解胰胆管合流异常(AJPBD)与病情的关系。结果126例患者保守治疗后肝功能检查中总胆红素(TB)、谷草转氨酶(AST)、谷丙转氨酶(ALT)、碱性磷酸酶(AKP)、γ-谷氨酰转肽酶(GGT)都明显降低,差异均有统计学意义(均P<0.05)。治疗后AJPBD组AST、ALT和GGT高于非AJPBD组,差异均有统计学意义(均P<0.05)。结论AJPBD可能是导致急性非梗阻性胆源性胰腺炎的重要因素。
Objective To investigate the pathogenesis of acute non-obstructive biliary pancreatitis. Methods Retrospective analysis of 126 cases of acute non-obstructive biliary pancreatitis in patients with clinical data and imaging data to understand the abnormal pancreaticobiliary duct (AJPBD) and the disease. Results The serum levels of total bilirubin (TB), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (AKP), γ-glutamyl transpeptidase ) Were significantly lower, the differences were statistically significant (P <0.05). The AST, ALT and GGT in AJPBD group were higher than those in non-AJPBD group after treatment (all P <0.05). Conclusion AJPBD may be an important factor leading to acute non-obstructive biliary pancreatitis.