目的　利用正交设计进行现场有选择性摄食试验 ,组合筛选灭鼠毒饵 ,以提高毒饵的接受性 ,并评价优选毒饵的灭鼠效果。方法　将糖精、花生油、食盐和白酒取 2～ 3种浓度选用L18(2 1× 37)正交表按设计组合后制备成 18种0 0 0 5 %溴敌隆颗粒试验毒饵 ,与对照毒饵一起在现场进行有选择性摄食试验 ,运用SPLM中文统计软件处理数据 ,优选配方。利用优选配方毒饵和对照毒饵进行现场灭鼠效果试验。结果　第 13号试验毒饵为优选毒饵 ,摄食系数为1 5 5 ,对照毒饵的摄食系数为 0 5 1。现场灭鼠试验 ,优选毒饵的灭鼠率为 10 0 % ,对照毒饵为 79 0 %。结论　应用正交设计组合筛选灭鼠毒饵 ,方法可行 ;优选的毒饵现场灭鼠效果好 OBJECTIVE: To select selective ingestion test by orthogonal design and to screen rodent poison bait in order to improve the acceptance of the bait and to evaluate the anti-rat effect of the preferred bait. Methods 18 saccharomyces, peanut oil, salt and white wine were selected and tested with 18 combinations of L18 (2 1 × 37) orthogonal test table and 18 kinds of 0 0 0 5% bromadiolone test bait were prepared and designed together with the control bait In the field of selective feeding test, using SPLM Chinese statistical software to process data, the preferred formula. On-site anti-rat effect test was conducted using the preferred formula bait and control bait. Results No. 13 test bait was the preferred bait, the feeding coefficient was 155 and the control bait had a feeding coefficient of 0 5 1. Field rodent tests, preferably bait rodent control rate was 100% control bait 79 0%. Conclusion Orthogonal design combinatorial screening rodent poison bait, the method feasible; the preferred poison bait field rodent effect is good