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目的研究不同体重妊娠期糖尿病(GDM)孕妇血脂水平及其与新生儿体重的关系。方法选取2015年1月-2016年8月在该院进行治疗的GDM孕妇120例,记作观察组。其中体重<50.5 kg者16例,50.5~65.0 kg者68例,≥65.0 kg者36例。另选取同期在该院接受产检的健康孕妇120例作为对照组,对比两组孕妇血脂水平,比较观察组不同体重患者的血脂水平以及对应的新生儿情况,分析观察组患者血脂水平与新生儿体重的相关性。结果观察组患者总胆固醇(TC)及甘油三酯(TG)水平均明显高于对照组(P<0.05)。两组低密度脂蛋白胆固醇(LDL-C)及高密度脂蛋白胆固醇(HDL-C)水平相比,差异无统计学意义(P>0.05)。观察组TC及TG水平随着体重的增加而上升,不同体重组间比较,差异有统计学意义(P<0.05)。观察组新生儿体重随着孕妇体重的增加而上升,组间差异有统计学意义(P<0.05)。根据Spearman法分析相关性发现,观察组患者的TC及TG水平均与新生儿体重呈正相关,与新生儿头围及胸围无明显相关性,且观察组患者LDL-C及HDL-C水平与新生儿体重、头围及胸围均无明显相关性。结论体重升高的GDM孕妇TC和TG水平也明显升高,且孕妇的TC及TG水平分别与新生儿体重呈正相关。
Objective To study the relationship between serum lipids in pregnant women with gestational diabetes mellitus (GDM) and their body weight. Methods A total of 120 pregnant women with GDM treated in our hospital from January 2015 to August 2016 were enrolled as observation group. Among them, 16 cases were weighing <50.5 kg, 68 cases were 50.5 ~ 65.0 kg, and 36 cases were ≥65.0 kg. Another 120 healthy pregnant women undergoing antenatal examination in the same period were selected as control group. The levels of serum lipids in two groups of pregnant women were compared. The levels of blood lipids and the corresponding newborns in different weight groups were compared. The level of serum lipids and body weight Relevance. Results The levels of total cholesterol (TC) and triglyceride (TG) in the observation group were significantly higher than those in the control group (P <0.05). There was no significant difference between the two groups in the levels of LDL-C and HDL-C (P> 0.05). The levels of TC and TG in the observation group increased with the increase of body weight. There was significant difference between different weight groups (P <0.05). The body weight of newborns in observation group increased with the weight gain of pregnant women, the difference was statistically significant (P <0.05). Spearman analysis of correlation found that the observation group of patients with TC and TG levels were positively correlated with the weight of newborns, neonatal head circumference and chest circumference were not significantly correlated, and the observation group of patients with LDL-C and HDL-C levels and new students Weight, head circumference and chest circumference were no significant correlation. Conclusion The levels of TC and TG in weight-bearing GDM pregnant women also significantly increased, and the levels of TC and TG in pregnant women were positively correlated with the weight of newborns.