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近年来，桥本甲状腺炎、甲状腺癌及桥本甲状腺炎合并甲状腺癌患病率均明显上升， HT合并甲状腺癌上升更明显。桥本甲状腺炎与甲状腺癌相关性的机制尚未明了，目前发现HT易发生甲状腺癌发病的机制及局部侵袭及远处转移的关系可能与免疫紊乱有密切关系，从免疫方面探讨桥本甲状腺炎和甲状腺癌之间关联，预测甲状腺癌的发生率，并对甲状腺癌的预后有临床指导意义。“,”In recent years, the incidences of Hashimoto’s thyroiditis (HT), thyroid cancer and HT with thyroid cancer were dramatically increased, and HT with thyroid cancer rose even faster. Although the correlation mechanism of HT and thyroid cancer was not clear yet, it was found that the relationship between HT and thyroid cancer and the relationship between local invasion and distant metastasis might closely relate to the immune disorder. To explore the correlation between HT and thyroid cancer from the aspect of im-munity, and to predict the incidence of thyroid cancer accordingly, play an important role in the prognosis of thyroid carcinoma.