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怎样才能使病人服药有效,长期以来就是医生伤脑筋的问题。举例来说,有人手上的刀伤处感染。医生给他开了口服抗生素,药物要起作用,必需经历艰难曲折的历程。首先,它要受到胃酸的作用,而后还要越过肠道的阻碍。通过这重重“围攻阻截”之后,只有很少一部分药物进入血液。就是这极少一部分药,到达发病处也只能是“蜻蜓点水”,不能久留。很快被分解排出体外。另一个复杂的情况是,无论口服还是注射,药液在血液中的浓度变化很大。一开头,浓度很高。几小时后,浓度急剧下降,达不到治疗的要求。为此,医生在开处方时,总要患者服用比实际所需剂
How to make patients take drugs effectively has long been a headache for doctors. For example, someone has a knife wound in his hand. The doctor gave him oral antibiotics, and the drugs had to work. They had to go through a difficult and tortuous course. First, it has to be affected by stomach acid and then has to pass over the intestinal barrier. After this heavy “siege”, only a small part of the drug enters the bloodstream. This is a very small part of the drug, and it can only be “swept water” when it reaches the pathogenesis. It cannot stay for long. Soon it was decomposed and excreted. Another complicated situation is that the concentration of the drug solution in the blood varies greatly, either orally or by injection. At the beginning, the concentration was very high. After a few hours, the concentration dropped sharply, failing to meet the treatment requirements. For this reason, when a doctor prescribes, he always takes the patient more than he actually needs.