本病近年渐受重视,包括Letterer-Siwe病(L-S病),Hand-Schuller-Christian病(H-S-C病)和嗜曙红肉芽肿三种综合征,均具有相同的病理形态,且可以相互转化,故今统称为组织细胞增多症X。病因不明,有感染和肿瘤学说,多认为系造血组织的界于反应性增生和肿瘤间的边缘性病变,约45～85％患者 The disease has received increasing attention in recent years, including the three syndromes of Letterer-Siwe disease (LS disease), Hand-Schuller-Christian disease (HSC disease), and erythrogranulomatous granuloma. All have the same pathology and can be transformed into each other. Therefore, this is collectively referred to as histicytosis X. The etiology is unclear, there are infections and oncology theory, mostly thought to be the boundary of hematopoietic tissue in reactive hyperplasia and borderline lesions, about 45 to 85% of patients