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目的 为了解纤维蛋白原溶解系统在急性白血病中的变化 ,期望早期发现 ,及时治疗。方法 采用发色底物法对各类急性白血病患者的血浆纤溶酶原 ,血浆激肽释放酶原 ,血浆总纤溶活性进行了检测。结果 急性白血病患者的纤溶酶原活性 ,激肽释放酶原活性均低于正常对照组 (P <0 0 0 1,P <0 0 1)。总纤溶活性高于正常对照组 (P <0 0 5 )。结论 在急性白血病患者复杂的出血原因中 ,纤溶亢进是其重要的因素之一。
Objective To understand the changes in the fibrinogen lysis system in acute leukemia, expect to find early, timely treatment. Methods The plasma plasminogen, plasma kallikrein and total fibrinolytic activity of various acute leukemia patients were detected by chromogenic substrate method. Results The levels of plasminogen and kallikrein in patients with acute leukemia were lower than those in the normal control group (P <0.01 1, P <0.01). The total fibrinolytic activity was higher than that of the normal control group (P <0.05). Conclusion Among the complicated causes of bleeding in patients with acute leukemia, fibrinolysis is one of the important factors.