With the rapid development of Internet of Things (IoT) technologies,the detection and analysis of malware have become a matter of concern in the industrial application of Cyber-Physical System (CPS) that provides various services using the IoT paradigm.Currently,many advanced machine learning methods such as deep learning are popular in the research of malware detection and analysis,and some achievements have been made so far.However,there are also some problems.For example,considering the noise and outliers in the existing datasets of malware,some methods are not robust enough.Therefore,the accuracy of malware classification still needs to be improved.Aiming at this issue,we propose a novel method that combines the conrentropy and the deep learning model.In our proposed method for malware detection and analysis,given the success of the mixture correntropy as an effective similarity measure in addressing complex datasets with noise,it is therefore incorporated into a popular deep learning model,i.e.,Convolutional Neural Network (CNN),to reconstruct its loss function,with the purpose of further detecting the features of outliers.We present the detailed design process of our method.Furthermore,the proposed method is tested both on a real-world malware dataset and a popular benchnark dataset to verify its learning performance.