论文部分内容阅读
目的:探讨氩离子凝固术联合埃索美拉唑治疗Barrett食管的临床效果。方法:选取本院2012年6月-2014年12月期间收治的Barrett食管患者40例作为研究对象,随机分为观察组和对照组各20例。给予对照组每日口服埃索美拉唑,观察组在接受氩离子凝固术治疗后,同样每天服用埃索美拉唑,剂量和疗程与对照组相同,观察比较两组的治疗效果。结果:观察组3、6、12个月时随访治疗总有效率均高于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:采用氩离子凝固术联合埃索美拉唑治疗Barrett食管,能有效消除Barrett黏膜和诱导鳞状上皮增生,操作简单、安全。
Objective: To investigate the clinical effect of argon plasma coagulation combined with esomeprazole in the treatment of Barrett’s esophagus. Methods: Forty patients with Barrett ’s esophagus treated in our hospital from June 2012 to December 2014 were selected as study subjects and randomly divided into observation group (20 cases) and control group (20 cases). The patients in the observation group were treated with esomeprazole orally on the same day. The dose and duration of treatment were the same as those in the control group. The therapeutic effects of the two groups were observed and compared. Results: The total effective rate of observation group at 3, 6 and 12 months after follow-up was higher than that of control group (P <0.05). The incidence of adverse reactions in the two groups, the difference was not statistically significant (P> 0.05). Conclusion: Argon ion coagulation combined with esomeprazole treatment of Barrett’s esophagus can effectively eliminate Barrett’s mucosa and induce squamous hyperplasia, which is simple and safe to operate.