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目的研究米非司酮联合中药对孕妇早孕蜕膜及绒毛的超微结构的影响 ,以探讨中西医结合抗早孕的机制。方法15例早孕妇女随机分为三组 ,每组 5例 :①西药组 ,服用米非司酮和米索前列醇 ;②中西结合组 ,在西药组基础上加服中药清热祛瘀汤剂 ;③对照组 ,实施人工流产术。用透射电镜及扫描电镜观察蜕膜、绒毛组织超微结构的变化。结果西药组及中西结合组均可见蜕膜变性及绒毛损害 ,以中西药结合组更严重、普遍。结论清热祛瘀汤与米非司酮有协同作用 ,能加重蜕膜变性及绒毛损害
Objective To study the effects of mifepristone combined with traditional Chinese medicine on pregnant women decidua and villus ultrastructure in order to explore the mechanism of Integrative Medicine anti-early pregnancy. Methods 15 cases of early pregnancy women were randomly divided into three groups of 5 patients: ① Western medicine group, taking mifepristone and misoprostol; ② Western combination group, on the basis of Western medicine plus Chinese medicine heat stasis soup Agent; ③ control group, the implementation of abortion. The ultrastructural changes of decidua and chorion were observed by transmission electron microscopy and scanning electron microscopy. results western medicine group and the combination of Chinese and Western decidua can be seen degeneration and villus damage to the combination of Chinese and Western medicine group is more serious and widespread. Conclusion Qingre Quyu Decoction with mifepristone have synergistic effects, can increase decidual degeneration and villus damage