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目的比较回、汉族胃癌患者血清内微量元素含量与胃癌发病的关系。方法采用原子吸收分光光度法和原子荧光法对回、汉族胃癌患者血清中Zn、Cu、Fe、Mg、Ca、Mn、Ni、Mo和Se元素含量进行检测,并用SPSS统计软件对实验结果进行χ2检验和组间t检验。结果结果表明,回族胃癌患者血清中Cu、Zn、Ni、Mn、Mo的含量均比汉族胃癌患者高,其中2组间Zn、Ni、Mn含量差异有统计学意义(P<0.05);Fe、Ca、Mg、Se的含量回族胃癌患者比汉族胃癌患者低,其含量在2组间差异均无统计学意义(P>0.05)。结论回、汉族胃癌患者血清中微量元素的含量存在差异,这可能与回、汉族不同的饮食习惯有关,因此针对胃癌病因的相应临床早期诊断和预防措施也应该注意人群特异性。
Objective To compare the serum levels of trace elements in Chinese patients with gastric cancer and the incidence of gastric cancer. Methods The contents of Zn, Cu, Fe, Mg, Ca, Mn, Ni, Mo and Se in the serum of Hui and Han nationality gastric cancer patients were detected by atomic absorption spectrophotometry and atomic fluorescence spectrometry. The experimental results were analyzed by SPSS software Test and t-test between groups. Results The results showed that the contents of Cu, Zn, Ni, Mn and Mo in patients with gastric cancer of the Hui nationality were higher than those of Han patients with gastric cancer, the contents of Zn, Ni and Mn in the two groups were significantly different (P <0.05) The contents of Ca, Mg and Se were lower in patients with gastric cancer than those in Han patients. There was no significant difference between the two groups in the content of Ca, Mg and Se (P> 0.05). Conclusion There are differences in trace elements in the serum between Han and Hui people with gastric cancer, which may be related to different dietary habits of Han and Hui people. Therefore, we should pay attention to the crowd-specificness in the early clinical diagnosis and preventive measures for the etiology of gastric cancer.