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目的 观察消炎愈创软膏的消炎抗菌促愈合作用 ,为临床应用提供依据。方法 用小鼠耳廓二甲苯致炎试验、疮疡试验观察消炎愈创软膏的消炎抗菌促愈合作用。结果 5 %剂量组能显著抑制二甲苯引起的小鼠耳廓肿胀 [5 %制剂肿胀度和对照组 :(3.0± 1.0 ) m g vs (7.1± 1.0 ) m g,P <0 .0 0 1];对金黄色葡萄球菌具有显著的抑制或杀灭作用 ,对大鼠局部创口有促进愈合的作用。
Objective To observe the anti-inflammatory, antibacterial, and healing effects of Xiaoyan Yuchuang Ointment for clinical application. Methods The anti-inflammatory, anti-bacterial, and anti-healing effects of Xiaoyan Yuchuang Ointment were observed with mouse auricle xylene inflammatory test and sore test. RESULTS: The 5%-dose group significantly inhibited xylene-induced ear swelling in mice [5% edema in the formulation and control group: (3.0 ± 1.0) mg vs (7.1 ± 1.0) mg, P <0.01]; The staphylococcus aureus has a significant inhibition or killing effect on the local wounds in rats to promote healing.