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为探讨中药“热毒清”对矽肺的治疗作用,用提纯及培养的5组巨噬细胞,以细胞学、细胞化学及扫描电镜法进行了动态观察。结果证实,SiO_2组细胞吞噬SiO_2粉尘后出现多种形态和一系列表面超微结构变化的特征,并远较中药组细胞迅速死亡和崩解。细胞内ACP和SDH活性等著低于中药组。本文认为,中药“热毒清”对矽尘致巨噬细胞毒性有明显的拮抗作用,进而可能具
In order to investigate the therapeutic effect of the traditional Chinese medicine “Huan Du Qing” on silicosis, the five groups of purified and cultured macrophages were observed dynamically by cytology, cytochemistry and scanning electron microscopy. The results confirmed that the SiO 2 group of cells swallowed SiO 2 dust after a variety of morphology and a series of changes in the characteristics of surface ultrastructure, and compared with the Chinese medicine group cells quickly died and disintegrated. The intracellular ACP and SDH activity were lower than those of the Chinese medicine group. This article believes that the traditional Chinese medicine “Hot Toxic Clearing” has obvious antagonistic effects on the macrophage toxicity caused by silica dust, and may have