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目的评价复方麝香按摩凝胶的抗炎、镇痛作用。方法通过角叉菜胶致大鼠足跖肿胀试验、二甲苯致大鼠耳廓肿胀试验,观察复方麝香按摩凝胶的抗炎作用;通过大鼠醋酸扭体法和热板法,观察复方麝香按摩凝胶的镇痛作用。结果复方麝香按摩凝胶能明显抑制角叉菜胶致大鼠足跖肿胀和二甲苯致大鼠耳廓肿胀;对醋酸致大鼠扭体反应有明显的抑制作用,可提高大鼠热痛阈值。结论复方麝香按摩凝胶有明显的抗炎、镇痛作用。
Objective To evaluate the anti-inflammatory and analgesic effect of compound musk massage gel. Methods Carrageenan-induced rat paw edema test, xylene-induced rat ear edema test to observe the anti-inflammatory effect of compound musk massage gel; acetic acid writhing method and hot plate method to observe the compound musk Massage Gel analgesic effect. Results Compound musk massage gel can significantly inhibit carrageenan-induced rat paw swelling and xylene-induced rat ear swelling; acetic acid-induced writhing in rats significantly inhibited, can increase the rat heat pain threshold . Conclusion Compound musk massage gel has obvious anti-inflammatory and analgesic effects.