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目的探讨黏膜硬化加固术对套扎后食管静脉曲张复发的预防作用。方法纳入257例食管静脉曲张破裂出血经套扎后曲张静脉消失的患者,将其随机的分为黏膜加固术组(139例)和单纯套扎术组(118例)。通过定期随访24～60个月,观察食管静脉曲张的复发率和并发症发生率。结果黏膜加固组静脉曲张复发率为43.9%,明显低于单纯套扎组(82.2%,P<0.05)。另外,黏膜加固术组行硬化加固治疗共达348次,并发症发生率为8.0%。结论黏膜硬化加固术能有效降低套扎术后食管静脉曲张复发,是一种能提高远期疗效的内镜治疗方法。
Objective To investigate the preventive effect of mucosal sclerosis on the recurrence of esophageal varices after ligation. Methods A total of 257 patients with esophageal variceal bleeding disappeared after ligation of varicose veins. The patients were randomly divided into mucosal reinforcement group (n = 139) and simple ligation group (n = 118). Through regular follow-up of 24 to 60 months, observe the esophageal varices recurrence rate and complication rate. Results The recurrence rate of variceal mucosa was 43.9%, significantly lower than that of simple ligation group (82.2%, P <0.05). In addition, the mucosal reinforcement group sclerosis treatment of up to 348 times, the complication rate was 8.0%. Conclusions Mucosal sclerosis can effectively reduce the recurrence of esophageal varices after ligation, which is an endoscopic treatment that can improve long-term efficacy.