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目的了解大竹县钩端螺旋体病(简称钩体病)两个集中暴发点流行病学特征,为制定防治措施提供科学依据。方法根据疫情报告,选取钩体病两个集中暴发点进行调查,用MAT法检测病人和蛙血清抗体;并分离培养钩体病原体。用夹夜法捕鼠,无菌采集鼠肾、猪肾、牛中段尿和蛙肾分离培养钩体病原体,分析钩体病流行病学特征和感染菌群情况。结果发病户数占总户数的68.13%;发病例数占总人数的28.41%;病人和宿主动物标本中检出阳性菌株51份,经鉴定以七日热群为主,占60.78%,其次分别为黄疸出血群、澳洲群、波摩那群、犬群,分别占29.41%、3.92%、3.92%、1.96%。结论病人和宿主动物感染钩体菌群复杂,应切实加强钩体病的监测,为制定钩体病防治方案提供科学依据。
Objective To understand the epidemiological characteristics of two concentrated outbreaks of Leptospirosis in Dazhu County (referred to as leptospirosis), and provide a scientific basis for making prevention and control measures. Methods According to the report of epidemic situation, two concentrated outbreaks of leptospirosis were selected for investigation. MAT antibody was used to detect the antibodies of serum of patients and frogs, and the pathogens of Leptospira were isolated and cultured. With the method of catching the night with the trap method, aseptic collection of rat kidney, porcine kidney, midgut urine and frog kidney were isolated and cultured leptospirosis pathogens, the analysis of leptospirosis epidemiological characteristics and infection flora. Results The number of affected patients accounted for 68.13% of the total number of cases; the number of cases accounted for 28.41% of the total number; 51 positive strains were detected in patients and host animal specimens, which were identified as seven-day fever group, accounting for 60.78% Respectively, jaundice bleeding group, Australia group, Pomona group, dog population, accounting for 29.41%, 3.92%, 3.92%, 1.96%. Conclusion The infection of leptospiridae in patients and host animals is complex, and the surveillance of leptospirosis should be strengthened. This provides a scientific basis for the development of prevention and control programs of leptospirosis.