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目的探讨胎盘多肽注射液对化疗患者升白细胞(WBC)的效果。方法选取2011年2月至2013年1月间化疗后肿瘤患者95例,随机分为观察组和对照组,观察组患者化疗后采用胎盘多肽注射液治疗,对照组患者采用升白安治疗。观察两组患者WBC计数变化情况、感染情况和临床疗效。结果观察组患者总有效和WBC计数平均值分别为95.8%和5.39×109/L,显著高于对照组的80.9%和3.68×109/L,差异有统计学意义(P<0.05)。观察组患者感染率和WBC<2.5×109/L的发生率分别为2.1%和8.3%,明显低于对照组的12.8%和27.7%,差异有统计学意义(P<0.05)。观察组患者WBC<1.0×109/L的发生率为0,虽低于对照组患者6.4%,但差异无统计学意义(P>0.05)。结论胎盘多肽注射液对化疗患者具有很好的临床效果,无明显的不良反应,能有效降低感染发生率。
Objective To investigate the effect of placental peptide injection on patients with chemotherapy-induced leukopenia (WBC). Methods Totally 95 patients with cancer after chemotherapy between February 2011 and January 2013 were randomly divided into observation group and control group. The patients in observation group were treated with placental peptide injection after chemotherapy and the patients in control group were treated with Shengbian An. WBC count changes, infection and clinical efficacy were observed in two groups. Results The total effective and WBC count in the observation group were 95.8% and 5.39 × 109 / L, respectively, which were significantly higher than those in the control group (80.9% and 3.68 × 109 / L, P <0.05). The incidence of infection and WBC <2.5 × 109 / L in observation group were 2.1% and 8.3% respectively, which was significantly lower than that in control group (12.8% and 27.7%, P <0.05). The incidence of WBC <1.0 × 109 / L in observation group was 0, which was lower than that in control group (6.4%), but the difference was not statistically significant (P> 0.05). Conclusion Placental peptide injection has a good clinical effect on patients with chemotherapy, no obvious adverse reactions, can effectively reduce the incidence of infection.