动脉粥样硬化是动脉壁的慢性炎症性疾病。免疫反应参与动脉粥样硬化形成的全过程。先天免疫反应的激活在动脉粥样硬化形成中具有重要作用。对先天免疫反应及模式识别受体在动脉粥样硬化形成中的作用进行研究不仅有助于理解动脉粥样硬化形成过程,而且还能通过直接干扰动脉粥样硬化形成中的炎症反应过程来提供抗动脉粥样硬化治疗的新方案、新策略。本文对此作一综述。 Atherosclerosis is a chronic inflammatory disease of the arterial wall. Immune response involved in the formation of atherosclerosis of the whole process. Activation of the innate immune response plays an important role in the development of atherosclerosis. Studying the role of innate immune responses and pattern recognition receptors in the development of atherosclerosis not only helps to understand the process of atherosclerosis but also provides an opportunity to directly interfere with the inflammatory response process in the development of atherosclerosis Anti-atherosclerosis treatment of new programs, new strategies. This article gives a summary of this.