论文部分内容阅读
目的:探讨窒息新生儿行为测定与头颅计算机断层扫描(CT)及振幅整合脑电图间的相关性及其临床意义。方法:选用86名窒息新生儿作为观察对象,按新生儿缺氧缺血性脑病(HIE)程度分成4组(HEIEO、HIE1、HIE2、HIE3),患儿生后7 d行新生儿行为测定,并行头颅CT、振幅整合脑电图等检查以评价新生儿神经损伤程度。结果:4组患儿后7 d行新生儿行为测定,并行头颅CT、振幅整合脑电图与7 d新生儿行为测定评分(NBNA)比较,HIE0与HIE1组间NBNA评分比较,差异无统计学意义(P>0.05),其余4组间NBNA评分、脑电图异常率、头颅脑白质CT值评分等指标比较,差异具有统计学意义(P<0.05),另患儿NBNA评分值与7 d时脑电图异常率呈负相关,同时与7 d时脑白质CT值呈正相关。结论:NBNA与脑电图、头颅CT等客观证据相关性高,有利早期发现及判断神经损伤情况,临床医师更能据此对患儿进行有针对性的干预,对临床有重要的指导意义。
Objective: To investigate the correlation between neonatal asphyxia and cranial computed tomography (CT) and amplitude-integrated electroencephalography (EEG) and its clinical significance. Methods: Eighty-six asphyxial newborns were selected as observation objects and divided into 4 groups (HEIEO, HIE1, HIE2, HIE3) according to the degree of neonatal hypoxic-ischemic encephalopathy (HIE) Parallel head CT, amplitude integration EEG and other tests to evaluate the degree of neonatal nerve injury. Results: Neonatal behavioral measurement was performed on the 7th day in 4 groups. Comparing the NBNA scores of head-brain CT, amplitude-integrated electroencephalogram and 7-day neonatal neonates, there was no significant difference between HIE0 and HIE1 groups (P> 0.05). There was significant difference between NBNA score, EEG abnormality rate and CT value of head white matter in the other 4 groups (P <0.05) EEG abnormality rate was negatively correlated with CT value of brain white matter at 7 d. Conclusion: NBNA is highly correlated with the objective evidences such as EEG and cranial CT, which is beneficial for early detection and judgment of nerve injury. Clinicians can better target children accordingly and have important guiding significance for clinical practice.