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癫痫的治疗目前仍以药物治疗为主。在过去的10余年中,有许多新药在中国上市并应用于临床,逐渐成为国内治疗癫痫的重要手段,尤其是耐药性癫痫的治疗。理想的抗癫痫药物(AEDs)一般应该具备以下条件:(1)比一线传统抗癫痫药物疗效更佳。(2)无严重不良反应。(3)无明显耐药性。(4)呈线性药代动力学,吸收迅速,清除完全,血浆蛋白结合率低。(5)能够迅速透过血-脑脊液屏障进入中枢神经系统,半衰期长。(6)使用简单,可以口
The treatment of epilepsy is still the main drug treatment. In the past 10 years, many new drugs marketed in China and applied to the clinic gradually became an important method for the treatment of epilepsy in China, especially the treatment of drug-resistant epilepsy. The ideal antiepileptic drugs (AEDs) generally should have the following conditions: (1) better than the first-line traditional antiepileptic drugs. (2) no serious adverse reactions. (3) no obvious resistance. (4) Linear pharmacokinetics, rapid absorption, complete removal, low plasma protein binding. (5) It can rapidly enter the central nervous system through the blood-cerebrospinal fluid barrier and has a long half-life. (6) easy to use, you can mouth