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Multiple organ dysfunction syndrome (MODS) or multiple organ failure (MOF) is a syndrome which is frequently related to shock and sepsis, and has been described as the most common cause of death in the noncoronary critical care unit. The potential pathogenesis of the septic and systemic inflammatory response syndrome (SIRS) response has been increasingly associated with the development and aggravation of MODS or MOF. And studies in this respect have also demonstrated that there is a higher risk of mortality associated with some specific organ systems when they are dysfunctional, thus leading to the failures of the liver, brain, lung, and kidney.1 The liver interacts with many other organ systems, and liver dysfunction may act collectively in the production of organ system dysfunction, thus finally ending up with MODS.2