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测定了114例阶结核病人血清β_2-微球蛋白(β_2-MG)值并与50例健康人组进行了比较,肺结核病灶活动者β2-MG值明显高于正常人(P<0.01),不同病变范围(病灶侵犯Ⅰ叶、Ⅱ叶、Ⅲ叶以上)之间比较血清β2-MG值依次升高,经抗痨治疗后病灶吸收,病情好转、稳定者,血清β_2-MG逐渐恢复正常。本结果提示血清β_2-MG值测定可作为肺结核病灶有无活动的指标之一,同时可作为估计肺结核炎症范围大小的参考指标。
Β2-MG was measured in 114 cases of tuberculosis patients and compared with 50 healthy people. Β2-MG of pulmonary tuberculosis activity was significantly higher than that of normal people (P <0.01) Serum β2-MG values increased in turn over the range of lesions (lesions Ⅰ, Ⅱ, and Ⅲ above). After anti-tuberculosis treatment, the lesions were absorbed, the condition improved, and the stability and serum β_2-MG gradually returned to normal . The results suggest that the determination of serum β_2-MG value can be used as one of the indicators of pulmonary tuberculosis activity, and can be used as a reference to estimate the size of pulmonary tuberculosis index.