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目的研究经雾化吸入给药治疗气管支气管内膜结核的疗效。方法采用随机分组,三联液组采用全身化疗加用异烟肼0.2g、阿米卡星0.2g、左氧氟沙星0.2g用20ml生理盐水稀释进行雾化吸入;并与单纯全身化疗组17例对照。结果三联液组总有效率为93.33%,而单纯全身化疗组的总有效率为70.58%,两组比较,P<0.05,有明显差异;两组均无明显毒副反应及并发症发生。结论三联液雾化吸入加全身化疗治疗气管支气管内膜结核疗效明显,优于单纯全身化疗,值得推广应用。
Objective To study the efficacy of nebulized inhalation for tracheobronchial endometrial tuberculosis. Methods The patients were randomly divided into three groups: systemic chemotherapy combined with isoniazid 0.2 g, amikacin 0.2 g and levofloxacin 0.2 g diluted with 20 ml normal saline for inhalation; and 17 cases were treated with systemic chemotherapy alone. Results The total effective rate of triple combined group was 93.33%, while the total effective rate of simple systemic chemotherapy group was 70.58%. There was significant difference between the two groups (P <0.05). No obvious side effects and complications occurred in both groups. Conclusion triple liquid atomization inhalation plus systemic chemotherapy tracheobronchial tuberculosis treatment significantly better than systemic chemotherapy alone, it is worth promoting the application.