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通过观察２８２５人次应用川芎嗪醋酸盐透析液血透患者透析前后ＳＣＲ、ＢＵＮ均值，及维持血透半年以上２６例慢性肾衰患者的血ＳＣＲ、ＢＵＮ、Ｎａ、Ｋ、Ｃａ、Ｃｌ、Ｐ均值，并与１９８５人次醋酸盐透析患者血透前后ＳＣＲ、ＢＵＮ均值，及维持透析半年以上１２例慢性肾衰患者的血ＳＣＲ、ＢＵＮ、Ｎａ、Ｋ、Ｃａ、Ｃｌ、Ｐ均值比较，结果：两组透析前血ＳＣＲ、ＢＵＮ均位无显著性差别（Ｐ＞０．０５），但透析后川芎嗪醋酸盐组ＳＣＲ、ＢＵＮ均值明显降低，统计学处理有非常显著性差别（Ｐ＜０．０１）；维持血透半年以上的ＳＣＲ、ＢＵＮ透析前均值亦比醋酸盐组均值低，统计学处理分别有非常显著（Ｐ＜０．０１）和显著性（Ｐ＜０．０５）差别。而血清电解质除Ｐ均值比较有显著性差别外，余均无显著性差别（Ｐ＞０．０５）。认为：应用具有活血祛瘀功用的川芎嗪醋酸盐液透析，与常规醋酸盐透析液比较，有显著提高血透效果的作用，且不会引起电解质紊乱。
The average SCR and BUN before and after hemodialysis in hemodialysis patients treated with Ligustrazine Acetate Dialysate were observed 2825 times, and the mean values of SCR, BUN, Na, K, Ca, Cl, and P in blood of 26 patients with chronic renal failure who maintained hemodialysis for more than half a year The mean SCR, BUN before and after hemodialysis in patients undergoing hemodialysis with 1985 visits, and the mean values of blood SCR, BUN, Na, K, Ca, Cl, and P in 12 patients with chronic renal failure who maintained dialysis for more than half a year were compared. There was no significant difference in the blood SCR and BUN between the groups before dialysis (P>0.05), but the SCR and BUN of the tetramethylpyrazine acetate group after dialysis were significantly lower, and there was a statistically significant difference (P<0. 01); The mean values of SCR and BUN before hemodialysis for hemodialysis for more than half a year were lower than those of the acetate group, statistically significant (P<0.01) and significant (P<0.05) differences. The serum electrolyte had no significant difference except the P mean (P>0.05). It is believed that the application of the Ligustrazine acetate solution for dialysis with the function of activating blood circulation can significantly improve the hemodialysis effect compared with the conventional acetate dialysate, and does not cause electrolyte disturbance.