论文部分内容阅读
目的:探讨急性脑梗死TOAST各分型纤维蛋白原水平(Fbg)的变化及松龄血脉康的干预效果。方法:将160例住院急性脑梗死患者随机分为治疗组和对照组,其中治疗组(松龄血脉康胶囊+疏血通注射液+拜阿司匹林组)85例,对照组(疏血通注射液+拜阿司匹林组)75例,检测各亚型的Fbg水平。结果:大动脉粥样硬化脑梗死(LAA)、心源性脑栓塞(CE)、小动脉闭塞脑梗死(SAO)血清Fbg与其他明确病因的脑梗死(OC)比较有统计学意义(P<0.05),LAA、CE、SAO与不明病因性脑梗死(UE)比较有统计学意义(P<0.05),LAA与SAO比较有统计学意义(P<0.05)。治疗组TOAST各型中LAA,CE,SAO治疗前后比较有显著差异(P<0.05);15 d后治疗组LAA,CE,SAO 3型与对照组比较有显著性差异(P<0.05)。结论:Fbg在大动脉粥样硬化型梗死、心源性脑栓塞、小动脉闭塞型脑梗死的发生发展中都发挥着重要作用。松龄血脉康可显著降低脑梗死患者的Fbg水平,可作为脑梗死的有效辅助治疗药物。
Objective: To investigate the changes of fibrinogen levels (Fbg) in TOAST with acute cerebral infarction and the intervention effect of Songling. Methods: A total of 160 hospitalized patients with acute cerebral infarction were randomly divided into treatment group and control group. Among them, 85 patients in the treatment group (Songlingxuemaikang capsule + Shuxuetong injection plus aspirin group), control group (Shuxuetong injection + Aspirin group) 75 cases, detection of subtypes of Fbg levels. Results: Serum Fbg in patients with atherosclerotic cerebral infarction (LAA), cardioembolic brain infarction (CE) and arteriovenous occlusive arterial occlusion (SAO) was significantly higher than those in other definite causes of cerebral infarction (P <0.05) ), LAA, CE, SAO and unknown cause cerebral infarction (UE) were statistically significant (P <0.05), LAA and SAO were statistically significant (P <0.05). The levels of LAA, CE and SAO in the treatment group were significantly different before and after LAA, CE and SAO treatment (P <0.05). The levels of LAA, CE and SAO 3 in the treatment group after 15 days were significantly different from those in the control group (P <0.05). Conclusion: Fbg plays an important role in the occurrence and development of atherosclerotic infarction, cardiogenic cerebral embolism and arteriolar occlusive cerebral infarction. Songling Kang can significantly reduce the level of Fbg in patients with cerebral infarction, can be used as an effective adjunctive therapy of cerebral infarction.