为探讨降低胃癌发病率的措施,用出生8天的大白鼠,以灌胃途径每鼠每天给予MNNG 150μg,连给3天。至断奶时将每窝幼鼠都按性别及体重随机分为3组,各喂1种用常用食品搭配的饲料,至给MNNG后的第300天,断颈处死,做病理学检验。结果发现胃的癌前组织改变的程度与体重的增长无关,而与免疫力的高低呈反比;饮食成分可影响胃癌的发展,通过合理组织饮食对胃癌的发展有抑制作用。 To investigate measures to reduce the incidence of gastric cancer, MNNG 150 μg/mouse was administered daily to rats for 3 days, using an 8-day-old rat. At the time of weaning, each litter of pups was randomly divided into 3 groups according to gender and weight, and each type of feed was fed with common foods until the 300th day after MNNG. The rats were killed by cervical dislocation and pathological examination was performed. The results showed that the degree of precancerous changes in the stomach had nothing to do with the increase of body weight, but was inversely proportional to the level of immunity; dietary components could affect the development of gastric cancer, and the development of gastric cancer could be inhibited by rational tissue diet.