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目的分析液基薄层细胞学检测(TCT)筛查热带地区宫颈癌的病变特征,探讨TCT在宫颈癌筛查中的价值。方法采用TCT检测12 231例宫颈细胞标本,根据TBS系统做出判读,并对结果进行回顾性分析。结果12 231例宫颈细胞标本中,细胞学阳性检出率从≥16岁组到≥80岁组,呈逐渐上升趋势(χ2=12.99,P<0.05)。活检确诊宫颈癌6例(鳞状细胞癌5例,腺癌1例),占0.05%(6/12 231),平均年龄58.50±9.33岁;CIN2~3占0.33%(40/12231),平均年龄41.35±8.95岁;CIN1占0.21%(26/12 231),平均年龄39.77±9.57岁。结论热带地区宫颈癌筛查呈现出低检出率和癌症发病高龄化的情况,因此,进行宫颈癌TCT筛查工作时要考虑不同的地区、不同人群的情况,适当延长热带地区筛查的终止年龄。
Objective To analyze the pathological features of cervical cancer in tropical areas by liquid-based TLCT and to explore the value of TCT in screening cervical cancer. Methods Totally 12 231 cervical cell samples were detected by TCT, and the interpretation was based on TBS. The results were retrospectively analyzed. Results Among 12 231 cervical cell samples, the positive rate of cytology was gradually increased from ≥16 years old to ≥80 years old (χ2 = 12.99, P <0.05). Biopsy confirmed 6 cases of cervical cancer (5 cases of squamous cell carcinoma, 1 case of adenocarcinoma), accounting for 0.05% (6/12 231), mean age 58.50 ± 9.33 years; CIN2 ~ 3 accounted for 0.33% (40/12231) Age 41.35 ± 8.95 years; CIN1 accounted for 0.21% (26/12 231), the average age of 39.77 ± 9.57 years. Conclusion Cervical cancer screening in the tropics shows a low detection rate and an aging incidence of cancer. Therefore, the screening of TCT in cervical cancer should take into account the situation in different regions and different populations, and appropriately extend the termination of screening in the tropics age.