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调节性T淋巴细胞(regulatory T cells,Treg)于1995年由Sakaguchi等~([1])发现。在外源性抗原的诱导下,主要通过分泌转录生长因子β(transform growth factor-β,TGF-β)和白细胞介素10(interleukin-10,IL-10)发挥免疫抑制作用~([2])。叉头状转录因子P3(fork head transcription factor p 3,Foxp3)是Treg细胞的
Regulatory T cells (Tregs) were discovered in 1995 by Sakaguchi et al. ([1]). Under the induction of exogenous antigens, the immunosuppressive effect is mainly through the secretion of transforming growth factor-β (TGF-β) and interleukin-10 (IL-10) . Fork head transcription factor P3 (Foxp3) is a Treg cell