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目的 评价99Tcm N 乙氧基 ,N 乙基氨荒酸钠 (N NOEt)门控心肌显像的临床应用价值 ,并与99Tcm 甲氧基异丁基异腈 (MIBI)进行比较。方法 2 0例受检者分为 2组 ,组 1:左室射血分数(LVEF)≥ 5 0 % ,共 13例 ,平均年龄 (4 9 9± 14 7)岁 ;组 2 :LVEF <5 0 % ,共 7例 ,平均年龄 (5 0 9± 12 9)岁。受检者静脉注射99TcmN NOEt92 5MBq后分别于 30和 12 0min行静息门控心肌断层显像 ,并计算心 /肺 (H/L)比值。组 2 6例、组 11例在 3d内行99Tcm MIBI门控心肌显像 ,将每例受检者的左室心肌分为 9个节段 ,以常规 4分法进行打分。结果 组 130及 12 0minH/L比值分别为 1 47± 0 47和1 5 9± 0 5 3(t=0 31,P >0 0 5 ) ,2次显像的LVEF、舒张末期容积 (EDV)和收缩末期容积 (ESV)差异无显著性 (P >0 0 5 )。组 2 30和 12 0minH/L比值分别为 0 72± 0 11和 0 89± 0 11(t=2 93,P <0 0 5 ) ,2次显像的LVEF ,EDV和ESV间差异无显著性 (P >0 0 5 )。 2组间的H/L比值和LVEF、EDV、ESV差异有显著性。NOEt与MIBI所得LVEF ,EDV和ESV值基本一致 (P >0 0 5 ) ,但NOEt的不正常节段数 (2 1个 )较MIBI(17个 )为多 ,两者的一致性为 93 6 5 % ,Kappa±s =0 87± 0 12 ,得分分别为2 0 0± 0 84(MIBI)和 2 38± 0 8
Objective To evaluate the clinical value of 99Tcm N ethoxy and N NOEt gated myocardial imaging and to compare with 99 Tcm methoxyisobutyl isonitrile (MIBI). Methods Twenty patients were divided into two groups. Group 1: LVEF ≥ 50%, a total of 13 patients (mean age 499 ± 14 7); Group 2: LVEF <5 0%, a total of 7 cases, the average age (59 ± 12 9) years old. Subjects underwent intravenous injection of 99TcmN NOEt92 5MBq at 30 and 120 min for resting gated myocardial tomography and the ratio of heart / lung (H / L) was calculated. Twenty-six patients in group (n = 11) underwent 99Tcm MIBI gated myocardial imaging in 3 days. The left ventricular myocardium of each subject was divided into 9 segments and scored by conventional 4-point method. Results The 130 min and 120 min H / L ratios were 1 47 ± 0 47 and 1 59 ± 0 5 3 (t = 0 31, P 0 05, respectively), LVEF and EDV And end-systolic volume (ESV) showed no significant difference (P> 0.05). There were no significant differences in LVEF, EDV and ESV between 2 30 and 12 0minH / L in the two imaging modalities of 0 72 ± 0 11 and 0 89 ± 0 11 (t = 2 93, P 0 05) (P> 0 0 5). H / L ratio and LVEF, EDV, ESV between the two groups were significant differences. The values of LVEF, EDV and ESV obtained by NOEt and MIBI were basically the same (P> 0.05), but the number of abnormal segments of NOEt was more than that of MIBI (17), and the consistency between the two was 93 6 5 %, Kappa ± s = 0 87 ± 0 12, scores of 200 ± 0 84 (MIBI) and 2 38 ± 0 8