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目的对临床微生物检验以及细菌耐药性进行监测,为临床抗菌药物的合理规范使用提供可靠依据。方法回顾性分析本院2014年10月1日-2015年10月1日临床各科室送检标本耐药菌株检出情况,分析各菌株对各类抗菌药物的耐药性。结果 ICU与临床外科检出菌株中耐药菌株检出率显著高于临床内科与临床儿科,差异均有统计学意义(P<0.05)。在检出耐药菌株中,凝固酶阴性葡萄球菌所占比例最高,为24.07%,其对多数抗菌药物的耐药性较高。耐药菌株对青霉素G的耐药性均较高,其中金黄色葡萄球菌高达99.00%。结论在临床用药中应给予敏感性高的药物提高治疗效果,合理规范的使用抗菌药物,降低细菌对抗菌药物的耐药性。
Objective To monitor clinical microbiology and bacterial resistance and provide a reliable basis for rational use of clinical antimicrobial agents. Methods A retrospective analysis of our hospital from October 1, 2014 to October 1, 2015 clinical departments of the detection of drug-resistant strains detected the situation, analysis of various strains of various antimicrobial resistance. Results The detection rate of drug-resistant strains in ICU and clinical surgical strains was significantly higher than that in clinical medicine and clinical pediatrics (P <0.05). In the detection of drug-resistant strains, coagulase-negative staphylococcus accounted for the highest proportion of 24.07%, the majority of antibacterial drug resistance higher. Resistant strains of penicillin G resistance were higher, of which Staphylococcus aureus up to 99.00%. Conclusion In the clinical medication should be given highly sensitive drugs to improve the therapeutic effect, rational use of antimicrobial agents, reduce bacterial resistance to antimicrobial agents.