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目的 探讨纳洛酮与醒脑静注射液联合治疗病毒性脑炎的疗效。方法 6 8例病毒性脑炎患儿随机平均分为两组 ,纳洛酮与醒脑静注射液联合用药组 (A组 )除给予综合治疗外 ,加纳洛酮 0 0 1～ 0 0 8mg·kg-1·d-1,醒脑静注射液 1ml·kg-1·d-1,使用 2～ 4d。常规治疗组 (B组 )给予综合治疗。结果 A组治愈 32例 ,占 94 12 % ,无一例死亡 ;B组治愈 2 5例 ,占 73 5 3% ,死亡 2例。两组比较差异有显著意义 (P <0 0 1)。结论 病毒性脑炎在综合治疗基础上给予纳洛酮和醒脑静注射液治疗安全有效。
Objective To investigate the curative effect of naloxone and xingnaojing injection in treating viral encephalitis. Methods Sixty-eight children with viral encephalitis were randomly divided into two groups. Naloxone combined with Xingnaojing injection (group A), except for combination therapy, kg-1 · d-1, xingnaojing injection 1ml · kg-1 · d-1, use 2 ~ 4d. The conventional treatment group (B group) given comprehensive treatment. Results A group of 32 cases were cured, accounting for 94 12%, no case of death; B group cured 25 cases, accounting for 73 5 3%, 2 died. There was significant difference between the two groups (P <0.01). Conclusions Viral encephalitis is safe and effective in the treatment of naloxone and xingnaojing injection on the basis of comprehensive treatment.