论文部分内容阅读
长期过度激活的肾素-血管紧张素系统(RAS)是高血压和房颤共同病理生理基础。血管紧张素受体阻滞剂(ARB)可以广泛抑制RAS系统,其降压之外预防房颤的作用受人关注。本文将ARB预防房颤的可能作用机制,以及在高血压患者房颤防治中的临床应用作一综述。
Long-term over-activation of the renin-angiotensin system (RAS) is a common pathophysiological basis of hypertension and atrial fibrillation. Angiotensin receptor blocker (ARB) can inhibit a wide range of RAS system, the anti-atrial fibrillation outside its antihypertensive effect of concern. This article reviews the possible mechanism of ARB in preventing atrial fibrillation and its clinical application in the prevention and treatment of atrial fibrillation in hypertensive patients.