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目的:探讨硝酸甘油联合脑垂体后叶素治疗支气管扩张大咯血的临床疗效。方法:选择50例支气管扩张大咯血的患者,随机分为试验组和对照组。试验组25例,应用硝酸甘油联合脑垂体后叶素联合治疗;对照组25例,采用垂体后叶素单药治疗作为对照组,对比2组临床疗效及不良反应。结果:治疗组总有效率96%,明显高于对照组80%,差异有统计学意义(P<0。05),且治疗组出现心悸,胸闷,高血压等不良反应明显少于对照组,差异有统计学意义(P<0。05)。结论:硝酸甘油联合脑垂体后叶素治疗支气管扩张大咯血,疗效优于脑垂体后叶素单药治疗,不良反应明显减少。
Objective: To investigate the clinical efficacy of nitroglycerin combined with pituitrin in the treatment of bronchiectasis massive hemoptysis. Methods: Fifty patients with bronchiectasis and hemoptysis were randomly divided into experimental group and control group. Experimental group of 25 cases, the application of nitroglycerin combined with pituitrin combined treatment; control group of 25 patients with pituitrin monotherapy as a control group, the clinical efficacy and adverse reactions in two groups. Results: The total effective rate of the treatment group was 96%, which was significantly higher than that of the control group (80%) (P <0.05). The adverse reactions such as heart palpitations, chest tightness and hypertension in the treatment group were significantly less than those in the control group The difference was statistically significant (P <0.05). Conclusion: Nitroglycerin combined with pituitrin treatment of bronchiectasis hemoptysis, the effect is superior to the pituitrin monotherapy, significantly reduced adverse reactions.